If concomitant here use is unavoidable, check serum cyclosporine concentrations and for indicators and symptoms of hepatotoxicity. Cyclosporine dose reductions may very well be required. think about therapy modification The changes may be really marked and could have a serious influence on the chance of atherosclerosis and coronary artery disorder

kramper. Desuden kan der opstå en stærk trang til atter at indtage stoffet. Ved ophør af behandlingen skal dosis derfor nedtrappes gradvist for at undgå abstinenser. Phenobarbital og andre epilepsimidler kan øge OxyContin® Depot sløvende og åndedrætshæmmende virkning. Advarselstrekanten viser, at medicinen virker sløvende, og at den ka